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For the 113th time, LSU and Ole Miss will share the same field when they meet on Saturday night. The 13th-ranked Tigers (4-1, 1-0) will host the No. 9 Rebels (5-1, 1-1), with the Magnolia Bowl Trophy on the line. LSU is coming off a bye, which followed four straight wins after a season-opening loss to USC. Ole Miss won its first four, then suffered a defeat to Kentucky before getting back in the win column with a victory over South Carolina last week.

The 2024 Magnolia Bowl will kick off at 7:30 p.m. ET from Tiger Stadium in Baton Rouge, La. The latest LSU vs. Ole Miss odds have the visiting Rebels as 3.5-point favorites, per SportsLine consensus. The over/under for points is 62.5, down from opening at 66.5. Before entering any Ole Miss vs. LSU picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread, and is 8-4 on top-rated picks over the past two weeks of this season. Anyone who has followed it has seen strong returns.

The model has set its sights on Ole Miss vs. LSU. You can head to SportsLine to see its picks. Here are several college football betting lines for the spreadmoney line and over/under:

  • LSU vs. Ole Miss spread: Ole Miss -3.5
  • LSU vs. Ole Miss over/under: 62.5 points
  • LSU vs. Ole Miss money line: Ole Miss -169, LSU +140
  • LSU vs. Ole Miss picks: See picks here
  • LSU vs. Ole Miss streaming: FuboTV (Try for free)

Why LSU can cover

From a purely passing perspective, there's been very little drop-off for LSU in going from Heisman winner Jayden Daniels to Garrett Nussmeier. The latter is actually averaging more passing yards per game than Daniels, and Nussmeier leads the SEC with 15 passing touchdowns. He threw for a career-high of 409 yards in his last game and showed off his legs as well, scoring two touchdowns on the ground. Also in that game, running back Caden Durham racked up 128 rushing yards, 89 receiving yard and touchdowns via both the ground and the air.

Durham has burst onto the scene in recent weeks and has accounted for 123.3 scrimmage ypg with five total touchdowns over his last three games alone. Out wide, the Tigers have three prolific pass-catchers in receivers Kyren Lacy and Aaron Anderson, plus tight end Mason Taylor. All three have at least 25 catches on the season, making LSU the only SEC team with three players who rank among the top 10 in the conference in receptions. See which team to pick here. 

Why Ole Miss can cover

These teams are nearly polar opposites when it comes to spread success, with Ole Miss having the overwhelming advantage. It is 5-1 against the spread this season, which is the best ATS record in the SEC. Meanwhile, LSU is just 1-4 ATS, the worst spread record in the conference. The Tigers failed to cover in their two games following byes last season, and since Brian Kelly took over in 2022, LSU is only 3-6 ATS against AP-ranked opponents.

On the field, Ole Miss has the defensive scheme to slow down the Tigers' offense. The Rebels already have four games this season in which they didn't allow the opponent to score a touchdown, after having three such games over the first four seasons of Lane Kiffin's tenure combined. They create turnovers and then capitalize off them as their +42 margin in points off turnovers is the fourth-best in FBS. Ranking even better is Ole Miss' 24 defensive sacks, which ranks first in the nation. Five different players have at least 2.5 sacks, led by Jared Ivey's five sacks, which ranks eighth in the country. See which team to pick here. 

How to make LSU vs. Ole Miss picks

The model has simulated Ole Miss vs. LSU 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits in over 50% of simulations. You can only see the pick at SportsLine.

So who wins LSU vs. Ole Miss, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Ole Miss vs. LSU spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.