The UNLV Rebels and Wyoming Cowboys face off in a key Mountain West Conference matchup at Allegiant Stadium in Las Vegas on Friday night. The Rebels (7-2, 4-1) are one game behind MWC leader Air Force and face the Falcons next week, so a victory Friday will keep them in the running for a title-game spot. Wyoming (6-3, 3-2) also could move into position for an outside chance if it can pull off an upset, though the Cowboys would likely need help. The teams have met twice since 2016, and Wyoming won both, most recently a 45-14 victory in Las Vegas in 2020.

Kickoff is set for 10:45 p.m. ET. The latest Wyoming vs. UNLV odds from the SportsLine consensus list the Rebels as 3-point favorites. The over/under for total points scored is set at 50. Before making any UNLV vs. Wyoming picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Wyoming vs. UNLV and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for UNLV vs. Wyoming: 

  • Wyoming vs. UNLV spread: Rebels -3
  • Wyoming vs. UNLV over/under: 50 points
  • Wyoming vs. UNLV money line: Cowboys +133, Rebels -158
  • WYO: Is 8-4 ATS in its past 12 as an underdog.
  • UNLV: Is 15-6 ATS since the start of last season.
  • Wyoming vs. UNLV picks: See picks at SportsLine
  • Wyoming vs. UNLV live stream: fubo (try for free)

Why UNLV can cover

The Rebels have the best scoring offense in the Mountain West, averaging 36.7 points per game. They also have the second-best rushing attack (199 yards) and are tied for second in FBS with 28 rushing touchdowns. UNLV's only losses are to No. 2 Michigan and MWC rival Fresno State, when they gave the ball away four times on the road. The Rebels have six turnovers in their other eight games. UNLV is 4-0 at home while Wyoming is 0-3 on the road.

The UNLV offense is led by running backs Vincent Davis Jr. (520 yards), Donavyn Lester (388) and Jai'Den Thomas (385). Lester and Thomas both have eight touchdown runs. The Cowboys also rely on the running game, but the UNLV defense's strength is defending the run. Wyoming averages less than 150 passing yards per game, with only Air Force's option attack ranking worse in the MWC. The Rebels yield 125 yards per game on the ground, third-best in the conference. See which team to pick here.

Why Wyoming can cover

The Cowboys have won the past two meetings by at least 30 points and have won five of the past six. Their defense should keep them in the game, as it ranks third in the MWC in scoring (25.1 points per game) and fourth in yards allowed (375.6). The unit has 16 takeaways, and linebacker Easton Gibbs is the lynchpin, with a team-high 81 tackles, 1.5 sacks, four passes defended and two forced fumbles. Wrook Brown has three interceptions and a fumble recovery. 

Quarterback Andrew Peasley is a dual threat and has 1,195 passing yards and 235 on the ground. The senior has accounted for 19 touchdowns and has thrown just four interceptions. Peasley had two TD passes last week, and Harrison Wayley rushed for 128 yards. Wyoming is seventh in the MWC in rushing (152.6 yards), and they'll try to make this a hard-nosed affair. Wyoming is plus-8 in turnover margin, tied for 10th-best in FBS, just behind UNLV (plus-9). See which team to pick here.

How to make UNLV vs. Wyoming picks

SportsLine's model is leaning Under on the point total. The model also says one side of the spread hits more than 50% of the time. You can only see the model's pick at SportsLine

So who wins Wyoming vs. UNLV, and which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.