As always, before we get to the perplexing injury situations you'll need to make decisions on before Sunday morning, here's a quick run-down of some other, less-intense Fantasy Football headlines:

Start your Jaguars: The Bengals are missing three offensive line starters and four defensive starters including two capable pass rushers (Carlos Dunlap, Carl Lawson) and two starting cornerbacks (Dre Kirkpatrick, William Jackson). Slot cornerback Darqueze Dennard will make his season debut, though. Leonard Fournette should be in all of your DFS lineups. Gardner Minshew and D.J. Chark should be in some, too. 

Offensive line injuries that matter: Colts guard and overall beast of a human Quenton Nelson (hip) showed up on Friday's injury report as a DNP. His absence would hurt the Colts run game quite a bit. ... Raiders giant right tackle Trent Brown is doubtful with a calf injury. ... Texans tackle Tytus Howard (knee) is out. ... The Cowboys anticipate having both Tyron Smith and La'el Collins back, improving their offensive line greatly. ... Two Jets starters -- left tackle Kelvin Beachum and left guard Kelechi Osemele are both not expected to play. Center Ryan Kalil is questionable and did not practice on Saturday. Missing all three would put a kiss of death on Sam Darnold's upside. 

Defensive injuries that matter: Falcons cornerback Desmond Trufant (toe) won't play for the second straight week. The Atlanta pass defense wasn't great with him and won't be any better without him. ... Colts slot corner Kenny Moore (knee) and safety Malik Hooker (knee) aren't expected to play, and starting cornerback Pierre Desir (hamstring) is questionable, opening up some promising matchups for the Texans passing game. ... The Dolphins are hopeful Xavien Howard (knee) will play, but let's be real, it's not going to matter much. ... Detroit will miss D-lineman Mike Daniels when Dalvin Cook runs all over the place on Sunday. Cornerback Darius Slay is questionable but should play. ... Redskins cornerback Josh Norman (thigh, hand) has been a liability this season but he might not play as he's questionable after missing practice all week.

NO New Orleans • #41
Age: 29 • Experience: 8 yrs.
Injury
Knee/ankle
Status
Out
It's a total bummer for Fantasy managers who continue to struggle with Kamara as a troubling first-round pick. After missing a week's worth of practice, Kamara will give way to Latavius Murray. The veteran should lead the Saints' charge with vets Dwayne Washington and Zach Zenner behind him. Murray has had 80 yards and/or a touchdown in 25 of 31 career games with at least 15 carries. Despite the tough matchup, Murray sets up as a good No. 2 running back. If you can't get him, other emergency running backs you could consider include Chase Edmonds (especially if David Johnson doesn't play), Alexander Mattison, Darrell Henderson and (gulp) Brandon Bolden.
ATL Atlanta • #21
Age: 30 • Experience: 7 yrs.
Injury
Quad
Status
not listed on report
Gurley will return on Sunday at the Falcons after a week's worth of limited practices. It's not known if he'll see as many snaps as he did in Week 5 (93%) or settle into an amount similar to what he played in Weeks 1 through 4 (a little over 70%). Regardless, he's averaged 15.6 touches per game with a pretty noticeable nose for the end zone. Five of six opponents against the Falcons have fielded a running back with 10-plus non-PPR points, so Gurley's good to go as a starter. Teammate Malcolm Brown (ankle) is doubtful, so we could see Darrell Henderson replace Gurley for about 5 to 7 touches.
NO New Orleans • #31
Age: 32 • Experience: 8 yrs.
Injury
Ankle
Status
Questionable
For the second week in a row, Johnson's on the injury report. But this time it's for an ankle problem that limited him in practice on Thursday and Friday. Cryptically, coach Kliff Kingsbury said if the game were on Friday, Johnson wouldn't be able to play. Chase Edmonds is the guy behind Johnson on the depth chart -- he's been seeing extended playing time the past two weeks, scoring in each game. Available in 36% of CBS leagues, he would see a ton of work against a struggling Giants run defense on Sunday if Johnson were ruled inactive. If you can't get him or Latavius Murray, other emergency running backs you could consider include Alexander Mattison, Darrell Henderson and (gulp) Brandon Bolden.
LV Las Vegas • #17
Age: 31 • Experience: 11 year
Injury
Toe
Status
Out
BUF Buffalo • #15
Age: 29 • Experience: 7 yrs.
Injury
Ankle, knee
Status
Questionable
ATL Atlanta • #82
Age: 30 • Experience: 5 yrs.
Injury
Concussion, chest
Status
Questionable
It's brutal that the Packers may not have any of their top three receivers for such a good matchup at home against the Raiders. Expect the Packers to roll with a big dose of Allen Lazard, Jake Kumerow and Darrius Shepherd with newcomer Ryan Grant. Lazard's gotten a lot of attention this week because he went from the bench to the end zone on Monday, but can be best described as a tall, physical dude with minimal explosiveness. He's not the very best receiver to race to waivers to get -- I'd still prefer Phillip Dorsett, Jamison Crowder or Adam Humphries in PPR.
JAC Jacksonville • #13
Age: 27 • Experience: 7 yrs.
Injury
Ankle
Status
Questionable
Kirk practiced all week on a limited basis and, for the second straight week, is being referred to as a game-time decision. It's been made clear by Cardinals coach Kliff Kingsbury that Kirk cannot play unless he's at 100%. You probably have a replacement receiver on your roster if you've been holding on to Kirk, who when healthy is a PPR dynamo. We'll know more about his status on Sunday morning.
LAC L.A. Chargers • #87
Age: 37 • Experience: 14 yrs.
Injury
Ankle
Status
Out
This one sort of snuck up on us: Cook didn't practice all week and won't have the chance to continue his touchdown streak at Chicago. That's just as well because the Bears have allowed just 10 touchdowns to tight ends since the start of the 2017 season. Odds are slim that Josh Hill (who's been playing more than Jared Cook over the past three weeks) will score. Better tight end replacements include Darren Fells, Jason Witten and Gerald Everett.
KC Kansas City • #5
Age: 27 • Experience: 6 yrs.
Injury
Ankle
Status
Questionable
Another week's worth of rest for Brown should mean another week of not playing football. Without him last week, the Ravens' leading receiver in Week 6 was Miles Boykin, who caught two passes for 28 yards on three targets. Willie Snead led the Ravens in targets with five. You're best served looking for a replacement receiver from another roster.

So who should you sit and start this week? And which surprising quarterback could lead you to victory? Visit SportsLine now to get Week 7 rankings for every position, plus see which QB is going to come out of nowhere to crack the top 10, all from the model that out-performed experts big time last season.