The New York Yankees will look to win their second series in a row and sixth over the past seven when they battle the Boston Red Sox in a key American League East matchup on Sunday Night Baseball. After losing the series opener 8-1 on Friday, Boston evened things up on Saturday with an 8-4 victory. The Yankees (50-23), who are 9-9 in the division, are 41-17 against right-handed pitchers in 2024. The Red Sox (36-35), who are 6-9 against AL East foes, are 28-23 against right-handed pitchers.

First pitch from Fenway Park in Boston is set for 7:10 p.m. ET. The Yankees are batting .254 as a team, fifth-best in MLB, while the Red Sox are hitting .250, ninth-best. New York is the -145 favorite on the money line (risk $145 to win $100) in the latest Yankees vs. Red Sox odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 9. Before making any Red Sox vs. Yankees picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 12 of the 2024 MLB season on a 129-105 run on top-rated MLB picks dating back to last season, and it has excelled on top-rated run-line picks during that span, going 20-8 (+809). Anybody following has seen huge returns.

Now, the model has set its sights on Yankees vs. Red Sox and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Red Sox vs. Yankees:

  • Yankees vs. Red Sox money line: New York -145, Boston +122
  • Yankees vs. Red Sox over-under: 9 runs
  • Yankees vs. Red Sox run line: New York -1.5 (+109)
  • NYY: The Yankees have hit the run line in 28 of their last 37 games (+23.55 units)
  • BOS: The Red Sox have hit the game total under in 16 of their last 24 games at home (+8.50 units)
  • Yankees vs. Red Sox picks: See picks at SportsLine

Why you should back the Red Sox

Left fielder Jarren Duran extended his hitting streak to six games on Saturday with a 2-for-5 performance, including a double, RBI and two runs scored. He was 3-for-5 with a double and an RBI in an 8-6 win over Philadelphia on Wednesday. In Thursday's 9-3 victory over the Phillies, he was 2-for-4 with two doubles and two RBI. In 71 games this season, Duran is hitting .275 with 21 doubles, 10 triples, five homers, 31 RBI and 47 runs scored.

Left fielder Tyler O'Neill has been productive of late. In Saturday's win over New York, he was 2-for-5 with a double, one RBI and two runs scored. He was 2-for-5 with a homer and three RBI in Thursday's win over Philadelphia. For the season, he has played in 48 games, hitting .253 with seven doubles, 12 homers, 23 RBI and 35 runs scored. See which team to pick here.  

Why you should back the Yankees

Right-hander Marcus Stroman (6-2, 2.82 ERA) will start for New York. He is coming off a 10-1 win at Kansas City on Tuesday. In that game, he pitched 5.2 innings, allowing four hits and three walks, while striking out one. He has won his last four decisions, and has allowed three or fewer earned runs in 10 of 14 starts. He has had good command for much of the season. In a 4-3 win over Oakland on April 23, he went 5.1 innings, allowing seven hits, three earned runs and one walk, while striking out nine.

Right fielder Juan Soto has been red hot, with five hits over the past four games, including a double, home run and two RBI. He homered in Saturday's loss to the Red Sox. For the season, Soto has played in 70 games, hitting .319 with 12 doubles, three triples, 18 homers, 55 RBI and 58 runs scored. In 14 career games against Boston, he has three homers and six RBI. See which team to pick here

How to make Red Sox vs. Yankees picks

SportsLine's model is leaning Over on the total, projecting 9.4 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks and analysis at SportsLine.

So who wins Yankees vs. Red Sox, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that's 129-105 on top-rated MLB picks, and find out.