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Soccer fans are in for a midweek treat with 12 matches set to be played in the MLS on Wednesday, May 29. Five games are scheduled to kick off at 7:30 p.m. ET, including Lionel Messi and Inter Miami CF hosting Atlanta United at Chase Stadium. Inter Miami sits atop the MLS standings with 34 points, but FC Cincinnati is just one point behind with a game in hand. Cincinnati will host Nashville SC in an Eastern Conference rivalry matchup on Wednesday at 7:30. 

Over in the Western Conference, several matchups could potentially shake up the standings, including Seattle Sounders vs. Real Salt Lake (10:30 p.m.) and LAFC vs. Minnesota United (9:45 p.m.). Before entering any MLS picks for Wednesday, May 29, be sure to see the MLS betting advice and score projections from SportsLine's soccer expert Brandt Sutton

Sutton, a former collegiate soccer player, has been SportsLine's top soccer editor for more than six years. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups and past performances to make the most-informed decisions possible, keeping his finger on the pulse of the game all over the globe.

Sutton finished 2022 as SportsLine's top soccer expert with a 165-130-2 mark, returning nearly $2,200 for $100 players. He was also profitable across multiple leagues in 2023, including the English Premier League, UEFA Champions League, FA Cup, Europa League, and more. 

Now, Sutton has analyzed the full MLS schedule for Wednesday, May 29, and locked in his exact score projections and MLS best bets. You can head to SportsLine now to see Sutton's picks

Top MLS predictions for Wednesday, May 29

One of Sutton's MLS score predictions is that Messi leads Inter Miami (-220) to a comfortable 3-1 victory at home against Atlanta United. Messi, Luis Suarez and Sergio Busquets were all rested on Saturday, but the Herons still walked away with a 2-1 win on the road against Vancouver. Miami's dynamic trio will be well-rested ahead of this clash, which doesn't bode well for an Atlanta side that has scored just one goal in their last four matches across all competitions. 

Messi has 10 goals and 12 assists this season and Suarez has found the back of the net 11 times in 2024. Inter Miami have scored 12 goals in their last four matches at home, while Atlanta United are winless in their last nine matches in MLS play. In addition, the Herons have won three straight at home, outscoring opponents 10-3 during that span. See the rest of Sutton's MLS score predictions here

How to get MLS picks, score predictions, best bets  

Sutton has locked in his exact score projections for every MLS match on Wednesday, as well as his three most confident best bets. They include an underdog winning outright and a high-scoring slugfest between two of the league's top teams. You can only see MLS score predictions and best bets at SportsLine.  

So which MLS picks can you make with confidence, and which underdog will pull off a shocking upset? Check out the latest MLS odds below, then visit SportsLine to see exact MLS score predictions for Wednesday, May 29, all from the insider who has constantly crushed his soccer picks. 

MLS odds, schedule for Wednesday, May 29 (all times p.m. ET)

Philadelphia Union vs. Toronto FC (7:30)
Philadelphia -185, Draw +310, Toronto +460

NY Red Bulls vs. Charlotte FC (7:30)
NY -185, Draw +300, Charlotte +490

Inter Miami vs. Atlanta United (7:30)
Miami -220, Draw +390, Atlanta +450 

CF Montreal vs. DC United (7:30)
DC +150, Draw +250, Montreal +160 

FC Cincinnati vs. Nashville SC (7:30)
Cincinnati -140, Draw +270, Nashville +380

Chicago Fire vs. Orlando City (8:30)
Chicago +155, Draw +230, Orlando +160 

Sporting KC vs. Vancouver Whitecaps (8:30)
Kansas City +115, Draw +250, Vancouver +200 

Austin FC vs. Portland Timbers (8:30)
Austin -105, Draw +250, Portland +250 

Houston Dynamo vs. Colorado Rapids (8:30)
Houston +100, Draw +260, Colorado +250

Seattle Sounders vs. Real Salt Lake (10:30)
Seattle +100, Draw +250, Salt Lake +240 

LA Galaxy vs. FC Dallas (10:30)
LA -210, Draw +330, Dallas +500 

LAFC vs. Minnesota United (10:45)
LAFC -210, Draw +360, Minnesota +490