The Philadelphia 76ers (31-21) and the Cleveland Cavaliers (35-16) square off in an Eastern Conference showdown on Monday. Cleveland has been on a tear to kick off 2024 as in the new year, the Cavs are 17-2. Meanwhile, Philadelphia is 2-8 over its last 10 games. Joel Embiid (knee), De'Anthony Melton (back) and Nicolas Batum (hamstring) are out for Philadelphia, with Tobias Harris (hip) listed as questionable. 

Tipoff is scheduled for 7 p.m. ET at Rocket Mortgage FieldHouse in Cleveland. The Cavs are 11-point favorites in the latest 76ers vs. Cavaliers odds via SportsLine consensus. The over/under for total points is 230. Before making any Cavaliers vs. 76ers picks, you'll want to see the NBA predictions and betting advice from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 17 of the 2023-24 NBA season on a sizzling 55-35 roll on all top-rated NBA picks this season, returning more than $1,800. Anyone following it has seen huge returns.

The model has set its sights on Sixers vs. Cavs. You can head to SportsLine now to see the picks. Here are several NBA betting lines and trends for Cavs vs. Sixers:

  • 76ers vs. Cavaliers spread: Cleveland -11
  • 76ers vs. Cavaliers over/under: 230 points
  • 76ers vs. Cavaliers money line: Cleveland -567, Philadelphia +413
  • PHI: The Philadelphia 76ers have hit the 4Q money line in 50 of their last 86 games
  • CLE: The Cleveland Cavaliers have won 34 of their last 47 games 
  • 76ers vs. Cavaliers picks: See picks at SportsLine

Why the Cavaliers can cover

Jarrett Allen is a long and athletic center who is a superb finisher in pick-and-roll situations. The Texas product is also a top-notch rim defender. Allen is seventh in the NBA in rebounds (10.6) and fifth in field-goal percentage (64.4%) with 15.5 points per game. Additionally, he's averaging 1.2 blocks per game, an in his last start, Allen had 18 points and 15 rebounds.

Guard Caris LeVert provides Cleveland with a slick ball handler. LeVert can take defenders off the dribble and plays with high energy on the defensive front. The Michigan product logs 14.7 points, 3.6 rebounds, and 4.3 assists per game. On Feb. 5 against the Sacramento Kings, LeVert had 17 points, six rebounds, and seven assists. See who to back at SportsLine.

Why the 76ers can cover

Guard Tyrese Maxey takes over the role as the main offensive weapon on the court with Embiid sidelined. The Kentucky product also has a reliable perimeter shot. Maxey averages 25.7 points with a team-high 6.4 assists per game. On Saturday, he tallied 28 points, nine rebounds, and seven assists.

Forward Harris (questionable) is another capable offensive threat. Harris owns a knockdown jumper from all three levels while being a consistent rebounder. The Tennessee product logs 17.7 points, six rebounds and 3.4 assists per game. He's scored 20-plus points in three of his last six games. See who to back at SportsLine.

How to make Cavaliers vs. 76ers picks

The model has simulated Sixers vs. Cavs 10,000 times and is leaning Over on the total, projecting 235 combined points. It also says one side of the spread well over 50% of the time. You can only see the picks at SportsLine.

So who wins 76ers vs. Cavs, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model on a 55-35 roll on top-rated NBA picks this season, and find out.